New research from a Danish consortium published in the Endocrine Society’s Journal of Clinical Endocrinology and Metabolism has shown that a natural compound which exists in chocolate, wine and other foods prevents bone loss in mice and rats. The compound, called resveratrol, may be promising for future osteoporosis research.
“Resveratrol, a natural compound found in red wine and grapes, increased spinal density in men with metabolic syndrome and could hold promise as a treatment for osteoporosis,” a recently press release from the Endocrine Society said.
Researchers discovered that men who took daily doses of resveratrol saw an increase in bone density compared to those who took the resveratrol placebo.
The Danish team also recorded that men who took the resveratrol pills also witnessed a 16 percent increase in alkaline phosphatase, an enzyme which increases in the presence of active bone formation.
A key fact for wine drinkers is that different wine regions produce wines of varying resveratrol levels.
A 2005 fact sheet released by Pennington Biomedical Research Center Nutrition concluded Spanish wines contain anywhere from about two milligrams of resveratrol per liter to about 12 milligrams per liter, whereas the global red wine average is about two milligrams to 7 milligrams.
Resveratrol is also found in chocolate, nuts and various fruits.
The Danish study is an extended, more thorough version of an earlier study which lasted only four weeks.
“Our data suggest that high-dose RSV supplementation positively affects bone, primarily by stimulating formation or mineralization,” the study concluded. “Future studies of longer duration comprising populations at risk of osteoporosis are needed to confirm these results.”
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